THE ORIGIN AND KINETICS OF MONONUCLEAR PHAGOCYTES
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چکیده
منابع مشابه
The Origin and Kinetics of Mononuclear Phagocytes
The origin and turnover of efferent populations of mouse mononuclear phagocytes has been described. Mononuclear phagocytes were defined as mononuclear cells which are able to adhere to glass and phagocytize. In vitro labeling studies with thymidine-(3)H showed that monocytes in the peripheral blood and peritoneal macrophages do not multiply and can be considered end cells in a normal, steady st...
متن کاملThe Effect of Glucocorticosteroids on the Kinetics of Mononuclear Phagocytes
The effect of glucocorticosteroids on the kinetics of mononuclear phagocytes, i.e., peripheral blood monocytes and peritoneal macrophages, was studied in normal mice, as well as in mice in which an inflammatory reaction was evoked in the peritoneal cavity. The administration of glucocorticosteroids resulted in a rapid decrease (within 3-6 hr) in the number of circulating monocytes, the duration...
متن کاملThe Differentiation of Mononuclear Phagocytes
The in vitro differentiation of homogeneous populations of monocyte-like cells from the unstimulated mouse peritoneal cavity is described. Under the conditions employed, a progressive increase in cell size occurs without significant cell division. This process is characterized morphologically by the accumulation of phase-dense and neutral red-positive granules, mitochondria, and lipid droplets....
متن کاملMurine and Human Mononuclear Phagocytes
as determined by vital staining, uptake of 2-deoxyglucose, and survival and replication in human fibroblasts. They are, however, rapidly killed by the addition of H202 and iodide under conditions in which control organisms are unaffected. We have used EPO bound to T. gondii to explore the role of peroxidase in the toxoplasmacidal activity of mononuclear phagocytes. Resident mouse peritoneal mac...
متن کاملDengue Viruses and Mononuclear Phagocytes
During the past two decades, dengue viruses have been a major cause of severe illness and death among children in tropical Asia (1). Dengue viruses are mosquito-borne flaviviruses which occur as four antigenically distinct types. Homotypic immunity is thought to be life long, but after a brief period of crossprotection, heterotypic infections occur and are accompanied by secondary-type antibody...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1968
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.128.3.415